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Author(s): Nikolaos Konstantinidis , Michele Pighi , Ismail Dogu Kilic , et al Added: 3 years ago
Coronary chronic total occlusions (CTOs) are identified in up to one third of patients with coronary artery disease referred for nonurgent coronary angiography,1,2 with an incidence increasing with age.3 Conceptually, you may argue that the motivation to reopen a totally blocked artery is not as strong as for subocclusive lesions, that have the potential to progress and cause acute events. The… View more
Author(s): Dean J Kereiakes Added: 3 years ago
Diabetes and the associated metabolic syndrome have reached epidemic proportions in many areas of the world.1,2 Atherosclerotic cardiovascular disease has been correlated with the presence, duration and severity of diabetes.3,4 Patients with diabetes have worse clinical outcomes following presentation for acute coronary syndrome (ACS)5,6 as well as following both surgical (coronary artery bypass… View more
Author(s): Aman Ali , Timothy A Sanborn Added: 3 years ago
Cardiogenic shock (CS) remains the leading cause of death among patients hospitalised for acute myocardial infarction (AMI), with mortality rates of approximately 50%.1 Even with the benefit of thrombolytic therapy and intra-aortic balloon pumps (IABPs), the in-hospital mortality rate of patients with CS from AMI was only lowered from 63 to 47% according to a report from the SHould we emergently… View more
Author(s): Chourmouzios A Arampatzi , Raul Moreno , Giuseppe Sangiorgi Added: 3 years ago
The introduction of bare-metal stents (BMS) provided a solution to the notable limitations of balloon angioplasty in patients undergoing percutaneous coronary intervention (PCI), notably acute occlusion, and improved the rate of reoccurrence of narrowing of the target vessel (restenosis) caused by smooth-muscle-cell proliferation with resultant neointimal hyperplasia. However, there is still… View more
Author(s): Alain Cribier Added: 3 years ago
Due to the ageing population and the consequent increased prevalence of aortic stenosis,1 the management of this disease in elderly patients, especially when associated with complex co-morbidities, is becoming an important issue for physicians. While surgical valve replacement remains the ‘gold standard’ treatment, operative mortality and morbidity increase with age and become significantly… View more