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Author(s): Kathryn Dawson , Tara L Jones , Kathleen E Kearney , et al Added: 3 years ago
Advances in transcatheter structural heart interventions and temporary mechanical circulatory support (MCS) have led to increased demand for alternative sites for large-bore vascular access.1 Percutaneous axillary artery (AA) access is an appealing alternative to standard femoral access when the patient has iliofemoral peripheral arterial disease (PAD), obesity or there is an expected device… View more
Author(s): Pavel Overtchouk , Thomas Modine Added: 3 years ago
This article aims to provide an updated comparative review, addressing the respective strengths and weaknesses of different alternative transcatheter aortic valve implantation (TAVI) approaches. The transfemoral (TF) access is favoured by international guidelines on TAVI because of its reported superiority to the transthoracic approach.1–3 In spite of the progress in miniaturisation of new… View more
Research Area(s) / Expertise:

Carotid Artery Disease

Peripheral Intervention

Inherited and Congenital Cardiac Conditions

Job title: Director of Complex Coronary Interventions
Personal History Dr Jaikirshan J. Khatri is a Cardiology Specialist and Director of Complex Coronary Interventions at Cleveland Clinic, Ohio. His clinical focus is on treatment of chronic total occlusions. In addition to his coronary practice, Dr Khatri performs peripheral, carotid and structural interventions and is facile in alternative access for large bore arterial catheters.7 In his… View more
Author(s): Uri Landes Added: 2 years ago
Dr Uri Landes (Rabin Medical Center, Petah Tikva, IL) discusses the results from the 2V-TAVR study. This retrospective cohort study used data from an international registry of 21 298 to assess incidence, causes and outcomes associated with urgent implantation of a supplementary valve during transcatheter aortic valve replacement. Questions 1. What was the rationale behind this study? 2. What was… View more
Author(s): Hannah McConkey , Bernard Prendergast Added: 3 years ago
Alain Cribier's determination in the 1980s to provide a definitive solution for high-risk surgical candidates with severe aortic stenosis was met with significant resistance. However, over many years transcatheter aortic valve implantation (TAVI) was developed and refined, leading to the first human procedure in April 2002 in France. Since this first description by Cribier et al.,1 there are now… View more
Author(s): Benjamin H Holland , Robert J Applegate Added: 3 years ago
Abstract Femoral access remains a vital route for many cardiac and non-cardiac procedures, including those involving the use of large delivery systems. In the common femoral artery access is extremely important to minimise complications and optimise use of closure devices. Dissatisfaction with haemostasis achieved by manual compression stimulated development of VCDs that provide quick and… View more
Author(s): Stephane Noble , Marco Roffi Added: 3 years ago
Since the first human transcatheter aortic valve implantation (TAVI)performed through an antegrade transfemoral approach (i.e. femoral venous access, transseptal puncture advancement of the device to the left ventricle and antegradely through the aortic valve), the venous approach has been abandoned and different arterial access routes such as the transfemoral, transapical, subclavian or direct… View more
Author(s): Andrea Pacchioni , Dimitris Nikas , Carlo Penzo , et al Added: 3 years ago
Transcatheter aortic valve implantation (TAVI) and endovascular aortic repair (EVAR) are increasingly being used as therapeutic options for patients with severe aortic stenosis ineligible for surgery and with aortic aneurysm with suitable anatomical features. Despite encouraging results from randomised studies and registries regarding the pursuit of endovascular treatment in selected patients,… View more