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Author(s):
David Antoniucci
Added:
3 years ago
In the setting of acute myocardial infarction (AMI), spontaneous and percutaneous coronary intervention (PCI)-related embolisation results in a decreased efficacy of mechanical reperfusion and myocardial salvage. Direct stenting without predilation may decrease embolisation and the incidence of the no-reflow phenomenon.1,2 More specific approaches to the problem of microvessel embolisation during…
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Author(s):
On Topaz
,
Allyne Topaz
,
Pritam R Polkampally
Added:
3 years ago
Plaque rupture and subsequent thrombus formation account for most acute myocardial infarctions (AMIs). Percutaneous coronary intervention (PCI) is considered the preferred treatment for ST-segment-elevation myocardial infarction (STEMI), for evolving non-STEMI (NSTEMI) and for rescue intervention post-thrombolytics.1 The main goals of primary and rescue PCI in AMI include restoration of a normal…
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Author(s):
Michael Tsang
,
Sanjit Jolly
Added:
3 years ago
Many advances have been made in the management of ST elevation myocardial infarction (STEMI) over the past three decades.1 This is owed to insight into role that thrombus has in the obstruction of the infarct-related artery (IRA) and the subsequent cascade of the myocardial ischaemia, cell oedema and myocardial necrosis. The institution of reperfusion therapy has revolutionised the care of…
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Martin Maresch
Job title: Senior Consultant Vascular and Endovascular Surgeon
Author
Author(s):
Krishnaraj S Rathod
,
Stephen M Hamshere
,
Tawfiq R Choudhury
,
et al
Added:
3 years ago
Primary percutaneous coronary intervention (PPCI) is the optimal treatment strategy for restoring coronary blood flow in the infarct related artery (IRA) and salvaging myocardium in patients with ST elevation myocardial infarction (STEMI).1,2 Despite this, PPCI fails to restore optimal myocardial perfusion in up to 40 % of patients despite restoring epicardial artery patency as evidenced by…
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Author(s):
Fizzah A Choudry
,
Roshan P Weerackody
,
Daniel A Jones
,
et al
Added:
3 years ago
Over the last few decades, primary percutaneous coronary intervention (PCI) has revolutionised the treatment of ST-elevation myocardial infarction (STEMI) with rapid recanalisation of the infarct-related epicardial vessel, resulting in smaller infarct size and a substantial reduction in adverse clinical endpoints.1,2 However, suboptimal myocardial reperfusion is documented to occur in a…
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Author(s):
Edwin Lee
,
Ajay J Kirtane
Added:
3 years ago
The outcomes of patients with ST-segment elevation myocardial infarction (STEMI) have improved in recent years with the more widespread adoption of definitive reperfusion therapies, including rapid recanalisation of the infarct-related artery with percutaneous coronary intervention (PCI). Nonetheless, despite the near universal restoration of normal epicardial flow following primary PCI for STEMI…
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Optimum Therapies for ST-Elevation Myocardial Infarction Managed with Primary Percutaneous Coronary…
Author(s):
Bruce R Brodie
Added:
3 years ago
Article
Author(s):
Michael Haude
Added:
3 years ago
Myocardial infarction (MI) is the leading cause of death worldwide in both men and women.1 An impending infarction is recognised by ST elevation, which is predominantly the result of an occlusive thrombosis in a coronary artery. An immediate goal in MI is to restore blood flow through the occluded coronary artery. Reperfusion is carried out using primary percutaneous coronary intervention (PCI)…
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