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Dual Antiplatelet Therapy After Drug-eluting Stent Implantation
Author(s): Giulia Magnani , Marco Valgimigli Added: 3 years ago
Dual antiplatelet therapy (DAPT), defined as the use of a P2Y12 receptor inhibitor (clopidogrel, ticagrelor or prasugrel) and aspirin, is required after percutaneous coronary intervention (PCI) with drug-eluting stents (DES).1 Although the use of DES has been shown to reduce the rate of restenosis as compared with bare-metal stents (BMS), there is concern that DES may be associated with a higher… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Mohammad Sahebjalal , Nick Curzen Added: 3 years ago
Antiplatelet therapy (APT) represents a major cornerstone in the secondary prevention of coronary artery disease, along with modifying patients’ risk factors. Furthermore, it has been clear, since early unsuccessful regimens, including warfarin and dypiridamole with aspirin, that it is APT that stops coronary stents from clotting off and causing stent thrombosis.1,2 Specifically, the requirement… View more

Anticoagulation

Prevention & Chronic Conditions
Shortened Dual Antiplatelet Therapy
Author(s): Kevin S Tang , Shoujit Banerjee , George Tang , et al Added: 4 months ago

Anticoagulation

MI/ACS
A3 - Veno-arterial ECMO Versus Impella™ Bleeding Complications in Cardiogenic Shock Patients on Dual Antiplatelet Therapy
Author(s): C Vandenbriele , J Wilson , A Baker , et al Added: 4 years ago

Heart Failure
EuroPCR 2021: Findings From the POEM Study
Author(s): Giulio G Stefanini Added: 2 years ago
Dr Giulio Stefanini (Humanitas Research Hospital, Milan, IT) discusses the findings from the multicentre POEM trial.The trial assessed the safety of the bioresorbable polymer-coated everolimus-eluting Synergy® stent in CAD patients undergoing PCI, followed by 1-month dual antiplatelet therapy (DAPT) in patients at high bleeding risk (HBR). Questions: 1. What is the POEM Study and what does it… View more

Anticoagulation

Intervention
BCIS ACI 2020: Update on DAPT
Author(s): Robert F Storey Added: 4 years ago
Prof Robert F Storey discusses the latest findings on dual antiplatelet therapy (DAPT) for the treatment of patients with coronary artery disease (CAD). Questions: 1.Could you summarise the key recent data being reported on DAPT? 2.Was any of this data surprising and does it need further research? 3.Do we need to review the role of aspirin in antiplatelet therapy? 4.Should this data impact… View more

Anticoagulation

Prevention & Chronic Conditions
Author(s): Anuj Gupta , Issam Moussa Added: 3 years ago
The treatment of atherosclerotic coronary artery disease (CAD) using percutaneous coronary intervention (PCI) is a well-established procedure that is performed over one million times a year in the US. The Achilles heel of PCI has been the development of neointimal hyperplasia within the stent, resulting in in-stent restenosis (ISR). Sirolimus-eluting stents (SES) provide a platform that in… View more

Intervention
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