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Author(s): On Topaz , Allyne Topaz , Pritam R Polkampally Added: 3 years ago
Plaque rupture and subsequent thrombus formation account for most acute myocardial infarctions (AMIs). Percutaneous coronary intervention (PCI) is considered the preferred treatment for ST-segment-elevation myocardial infarction (STEMI), for evolving non-STEMI (NSTEMI) and for rescue intervention post-thrombolytics.1 The main goals of primary and rescue PCI in AMI include restoration of a normal… View more

MI/ACS

Intervention
Dominick J Angiolillo
Research Area(s) / Expertise:

Thrombosis, embolism & bleeding

Intervention

Coronary Artery Disease and Myocardial Infarction

 Job title: Professor & Chief
Dr Dominick Angiolillo graduated from the Catholic University of the Sacred Heart Medical School in Rome, Italy and pursued training in interventional cardiology at the Complutense University of Madrid in Spain and received his Ph.D. in cellular and molecular cardiology.Dr Angiolillo is board-certified in internal medicine, cardiovascular disease and interventional cardiology. In 2004, Dr… View more
SUGAR: Amphilimus-eluting Stents VS Zotarolimus-eluting Stents in Patients With DB
Author(s): Rafael Romaguera Added: 2 years ago
In this short interview, Dr Rafael Romaguera (University of Barcelona, SP) discusses the findings from the SUGAR trial.This randomized head-to-head trial aimed to compare Cre8 EVO stents to a contemporary drug-eluting stent (DES) in patients with diabetes (DM) and coronary artery disease. The trial, first presented at TCT 2021, demonstrated that Cre8 EVO stents were non-inferior to Resolute Onyx… View more

Prevention & Chronic Conditions
Author(s): Paul Guedeney , Birgit Vogel , Roxana Mehran Added: 3 years ago
Dual antiplatelet therapy (DAPT) including aspirin and a P2Y12 inhibitor is the current gold standard for the treatment and mid-term secondary prevention of acute coronary syndrome (ACS).1–4 However, despite the use of potent P2Y12 inhibitors such as ticagrelor or prasugrel, patients remain at high ischaemic risk after ACS. More specifically, in the prasugrel treatment arm of the TRial to Assess… View more

Anticoagulation

MI/ACS
Percutaneous Coronary Intervention in Older People
Author(s): Sami A Omar , Adam de Belder Added: 3 years ago
There will be guidelines about the optimal management of most clinical situations. It makes decision making in medicine more universal, but often you have to think about all of the awkward situations that sit outside the guidelines. One neglected area of research involves the management of illness in older people. The older patient is often not included in trial protocols, and so a well of… View more

Vascular Disease and Surgery

Imaging & Diagnostics
Author(s): Alfredo Galassi , Aaron Grantham , David Kandzari , et al Added: 3 years ago
Section A Coronary Chronic Total Occlusions – Prevalence and Pathophysiology A chronic total occlusion (CTO) is defined as a completely occluded coronary artery with no antegrade flow (thrombolysis in myocardial infarction [TIMI] 0 flow) for at least three months.1 CTOs are present in 15–30 % of patients undergoing coronary angiography.2–5 In a Canadian prospective registry of 14,439 patients… View more

Heart Failure

MI/ACS
Angiographic Characteristics in Older NSTEACS Patients
Author(s): Benjamin Beska , Hanna Ratcovich , Alan Bagnall , et al Added: 1 year ago

MI/ACS

Intervention
Author(s): Bob Kloner , Kiyotake Ishikawa Added: 3 years ago

MI/ACS
The STEMI Door-to-Unload (DTU) Clinical Trial Programme
Author(s): Navin K Kapur Added: 2 months ago

Intervention
Author(s): Bruce R Brodie Added: 3 years ago
Abstract This article reviews optimum therapies for the management of ST-elevation myocardial infarction (STEMI) with primary percutaneous coronary intervention (PCI). Optimum anti-thrombotic therapy includes aspirin, bivalirudin and the new anti-platelet agents prasugrel or ticagrelor. Stent thrombosis (ST) has been a major concern but can be reduced by achieving optimal stent deployment, use… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions