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Author(s): Peter Mortier , Heleen MM van Beusekom , Matthieu De Beule , et al Added: 3 years ago
Incomplete stent apposition (ISA) or stent malapposition is the lack of contact between stent struts and the underlying arterial wall. ISA has been associated with significantly higher levels of thrombus deposition1 and is typically assessed by intravascular imaging techniques such as optical coherence tomography (OCT) and intravascular ultrasound (IVUS).2–4 These imaging modalities are useful to… View more

Imaging & Diagnostics

Intervention
Author(s): Nicolas Foin , Eduardo Alegria-Barrero , Ryo Torii , et al Added: 3 years ago
Drug-eluting stents (DESs) have contributed to a significant lowering of the incidence of restenosis and target vessel revascularisation (TVR) in bifurcations.1–4 A randomised study of bifurcation lesions using sirolimus-eluting stents revealed restenosis rates of only 4 % in the main branch (MB) and a TVR rate as low as 8.2 % at six-month follow-up,2 a marked improvement over that in historical… View more

Prevention & Chronic Conditions
Author(s): Tom Adriaenssens , Giovanni J Ughi , Jan Dhooge , et al Added: 3 years ago
In the bare metal stent (BMS) era, several intravascular ultrasound(IVUS) studies have validated the strategy of reducing in-stent restenosis rates by a strict adherence to an optimal stent implantation technique, predominantly by avoiding stent underexpansion.1 In a first phase after the introduction of drug-eluting stents(2003), the spectacular reduction in restenosis rates, based on… View more

Imaging & Diagnostics

Intervention
Author(s): Viktor Kočka , Petr Widimsky Added: 3 years ago
Terminology When the first-in-human implantation of a bioresorbable device into the coronary artery was reported in 2007, the term ‘fully bioabsorbable stent’ was used.1 Later, in 2011, Onuma and colleagues explained that the term ‘bioresorbable’ provides a more precise description of the complete cleavage of macromolecules to small molecules with total elimination and the term ‘scaffold’ was… View more

MI/ACS

Intervention
OCT-guided Percutaneous Coronary Intervention in Bifurcation Lesions
Author(s): Luca Longobardo , Alessio Mattesini , Serafina Valente , et al Added: 3 years ago
Coronary artery bifurcation lesions are treated in 15–20% of percutaneous coronary intervention (PCI) procedures and are still plagued by worse outcomes.1 This is in spite of recent significant advancements in stent technology in general and in bifurcation stenting techniques in particular. Conventional angiography provides only limited information about bifurcation anatomy, plaque distribution… View more

Intervention
Author(s): Nienke S van Ditzhuijzen , Jurgen M Ligthart , Nico Bruining , et al Added: 3 years ago
The indications for percutaneous coronary intervention (PCI) have expanded steadily during the past years. After the days of the revascularisation of obstructive coronary artery disease (CAD) by balloon angioplasty,1 the introduction of coronary stents has essentially contributed to PCI being one of the most frequently performed invasive therapeutic procedures worldwide. Bare metal stents (BMS)… View more

Imaging & Diagnostics

Intervention
Author(s): Angela Hoye Added: 3 years ago
The coronary tree is comprised of arteries which divide into ever smaller branches to supply the myocardium. This means that the diameter of the vessel proximal to a bifurcation is always larger than the diameter of the main vessel distal to the bifurcation. The proximal optimisation technique (POT) was proposed by Dr Olivier Darremont as a technique to compensate for this difference in diameters… View more

Intervention
Author(s): Francesco Prati , Fabrizio Imola Added: 3 years ago
Many experts would agree that the concept of looking at vessel architecture from the inside using intracoronary probes, instead of simply relying on the angiographic vessel cast, is an elegant way to practise interventional cardiology in order to decide whether to treat a coronary artery and to guide coronary intervention. The historical development of stents neatly exemplifies this notion: the… View more

Imaging & Diagnostics

Intervention
Clinical Impact of Stent Design
Author(s): Rebecca L Noad , Colm Hanratty , Simon J Walsh Added: 3 years ago
As the role of percutaneous coronary intervention (PCI) has evolved, inevitably, so too has the technology associated with this specialty. Initially, plain old balloon angioplasty (POBA) was developed as a strategy to ‘stretch’ focal stenoses within the coronary arteries leading to a relief from ischaemia and angina. Whilst potentially of great benefit to some patients, POBA was beset by a series… View more

Intervention
Author(s): Dominic J Allocco , Mary V Jacoski , Barbara Huibregtse , et al Added: 3 years ago
Advances in drug-eluting stent technology have continued to improve clinical outcomes for patients undergoing percutaneous coronary intervention (PCI). The development of the platinum– chromium (PtCr) alloy and Element™ stent architecture (or platform) is the result of more than eight years of research and development by Boston Scientific Corporation (BSC; Natick, MA, US) and builds on a pedigree… View more

Prevention & Chronic Conditions