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Author(s): Fabrizio Fanelli , Emanuele Boatta , Pierleone Lucatelli , et al Added: 3 years ago
Stroke is the third leading cause of death and permanent disability in the US and Europe. It is estimated that there are over 700,000 new cases of stroke each year in the US, of which 20–30% are thought to be secondary to carotid thromboembolic disease.1 In the last few years, carotid artery stenting (CAS) has significantly expanded as an alternative treatment to the conventional surgical carotid… View more

Prevention & Chronic Conditions
Author(s): Andrew Archbold Added: 3 years ago
Patients who undergo coronary artery stenting require dual antiplatelet therapy (DAPT) in order to reduce their risk of stent thrombosis. Long-term oral anticoagulation (OAC) is indicated for the primary and secondary prevention of thrombotic events in patients with atrial fibrillation (AF), mechanical heart valves, intra-cardiac thrombus, venous thromboembolic disease and some hypercoagulable… View more

Anticoagulation

Prevention & Chronic Conditions
Percutaneous Closure of Patent Foramen Ovale
Author(s): Stefan Stortecky , Stephan Windecker Added: 3 years ago
Cerebrovascular events are associated with high rates of morbidity and mortality and are considered the global second leading cause of death.1 The majority of strokes are ischemic, although the etiology remains unknown in a considerable number of patients,2 commonly referred to as “non-defined” or “cryptogenic.”3 Data from epidemiologic studies point towards a relevant association between the… View more

Standards & Guidelines

Prevention & Chronic Conditions
Author(s): Grégory Ducrocq , Dominique Himbert , Eric Brochet , et al Added: 3 years ago
Aortic stenosis (AS) is currently the most frequent native valve disease in Europe and is most often seen in elderly patients with co-morbidities.1 Valve replacement is the definitive therapy for patients with severe AS who have symptoms or objective consequences such as left ventricular (LV) dysfunction.2,3 However, the risk of surgery may be higher in elderly patients with significant co… View more

Vascular Disease and Surgery

Intervention
Author(s): Herbert G Kroon , Nicolas M Van Mieghem Added: 3 years ago
Over the past decade, transcatheter aortic valve implantation (TAVI) has become the treatment of choice for elderly patients with symptomatic severe aortic stenosis at high risk for death or complications with conventional surgical aortic valve replacement.1–4 Recent studies and clinical practice confirmed TAVI feasibility in patients with a lower risk profile who are typically younger and have a… View more

Vascular Disease and Surgery

Intervention
Author(s): Ren Jie Yao , Matheus Simonato , Danny Dvir Added: 3 years ago
In the context of an ageing population, care for valvular disease is becoming an increasingly important field. A recent large-scale population-based study found the prevalence of valvular disease to be 8.5 % in the 65–74-year-old group and 13.2 % in those over 75 years. 1 While mechanical surgical valves are more durable, bioprosthetic valves are often used as they are less thrombogenic and do… View more

Vascular Disease and Surgery

Intervention
Author(s): Deepak Natarajan Added: 3 years ago
Primary percutaneous coronary intervention (PCI) is the treatment of choice in the management of acute ST-segment elevation myocardial infarction (STEMI). It has been constantly observed that, despite restoring good epicardial flow with PCI, myocardial perfusion at the cellular level remains impaired in nearly 50 % of STEMI patients. This led to the development of a new class of antiplatelet… View more

Anticoagulation

MI/ACS
Author(s): Hannah McConkey , Bernard Prendergast Added: 3 years ago
Alain Cribier's determination in the 1980s to provide a definitive solution for high-risk surgical candidates with severe aortic stenosis was met with significant resistance. However, over many years transcatheter aortic valve implantation (TAVI) was developed and refined, leading to the first human procedure in April 2002 in France. Since this first description by Cribier et al.,1 there are now… View more

Vascular Disease and Surgery

Standards & Guidelines
Author(s): Antonio L Bartorelli , Claudio Tondo Added: 3 years ago
On average, every 20 seconds someone in the US1 or in Europe2 has a stroke. This adds up to a total of about 1.7 million strokes per year in these two continents, affecting about 0.22% of the population each year. In the US alone, every four minutes someone dies from stroke, yielding a total mortality of about 140,000 deaths per year. As a result, stroke is the world’s third leading cause of… View more

Prevention & Chronic Conditions
View from the Thoraxcenter: TCT 23 Late-breaking Science Preview
Author(s): Joost Daemen , Nicolas M Van Mieghem Added: 6 months ago
What's hot at TCT 2023? In this episode of View from the Thoraxcenter, Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcenter, Erasmus MC, NL) preview the late-breaking data presented at TCT 2023. With their dynamic analysis, these anticipated trials are placed in context, highlighting the real-world implications tied to the data releases. Top trials covered: 00:31 - 02:12: PARTNER 3 Low… View more

Intervention