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Author(s): Stuart J Head , Ad JJC Bogers , A Pieter Kappetein Added: 3 years ago
Valvular Heart Surgery The field of cardiac surgery is urgently in need of new anticoagulant agents. Approximately 300,000 prosthetic valves are implanted yearly, after which lifelong anticoagulation therapy is mandatory as thromboprophylaxis. To date, vitamin K antagonists (VKAs), such as warfarin, remain the only licensed agents to prevent mechanical valve-induced thromboembolic events but… View more

Anticoagulation

Vascular Disease and Surgery
Controversies Regarding Subclinical Leaflet Thrombosis After TAVR
Author(s): Jolanta Siller-Matula , Mamas A Mamas , Kimberly Atianzar , et al Added: 3 years ago
A substantial number of patients develop a subclinical leaflet thrombosis (SLT) after transcatheter aortic valve replacement (TAVR). The thrombus forms on the leaflets, which can lead to valve dysfunction and possibly to early valve degeneration. Multidetector computed tomography is the most sensitive imaging technique at detecting SLT. Patients on antiplatelet drugs are at higher risk to… View more

Imaging & Diagnostics

Intervention
Author(s): Philippe Garot , Bertrand Cormier , Jérôme Horvilleur Added: 3 years ago
Left atrial appendage closure (LAAC) has been shown to be non-inferior to warfarin in decreasing the risk of stroke and systemic embolism in patients with AF.1–3 In addition to peri-procedural complications (tamponade, device migration, procedure-related stroke or embolism, and vascular complications), there has been growing concern recently about the occurrence of late complications, especially… View more

Anticoagulation
Author(s): Luca Testa , Azeem Latib Added: 3 years ago
Leaflet motion abnormalities (LMAs) are a relatively new entity in the field of transcatheter aortic valves (TAVs).1–4 They can be associated with the thrombosis of the bioprosthesis (TAVT), often leading to dramatic clinical scenarios1 or, on the other hand, they can result in a hypoattenuated leaflet thickening (HALT) and/or reduced leaflet motion (RELM), both usually associated with gradients… View more

Vascular Disease and Surgery

Intervention
Antoni Martínez-Rubio
Research Area(s) / Expertise:

Atrial Fibrillation

Coronary Artery Disease and Myocardial Infarction
Dr Antoni Martinez Rubio , Jefe de Servicio de Cardiología del Hospital Parc Taulí de Sabadell (Barcelona, España).Dr Martínez-Rubio is on the Editorial Board of European Cardiology Review. View more
Author(s): Paul Guedeney , Birgit Vogel , Roxana Mehran Added: 3 years ago
Dual antiplatelet therapy (DAPT) including aspirin and a P2Y12 inhibitor is the current gold standard for the treatment and mid-term secondary prevention of acute coronary syndrome (ACS).1–4 However, despite the use of potent P2Y12 inhibitors such as ticagrelor or prasugrel, patients remain at high ischaemic risk after ACS. More specifically, in the prasugrel treatment arm of the TRial to Assess… View more

Anticoagulation

MI/ACS
Controversies Regarding Subclinical Leaflet Thrombosis After TAVR
Author(s): Mamas A Mamas , Kimberly Atianzar , Poonam Velagapudi , et al Start date: Nov 19, 2020

Imaging & Diagnostics

Intervention
Job title: Cardiothoracic Surgeon
Mr Adrian Pick graduated in 1993, from the Melbourne University Medical School then completed overseas fellowships at the MAYO clinic and the Toronto General Hospital. His interests include minimal access surgery for thoracic and cardiac surgery with emphasis on mitral valve repair and limited access aortic valve replacement. He is also committed to maximizing surgical treatment for both… View more
Job title: Professor of Cardiovascular Medicine
Prof Felicita Andreotti is a tenured Professor and Medical Director at the Gemelli IRCCS Hospital and Catholic University in Rome, Italy, where she currently coordinates cardiovascular research within the Scientific Directorate.Prof Andreotti gained her MD and two specialties - in respiratory and cardiac diseases - from the University of Strasbourg, France, and then Pisa, Italy. During her PhD… View more