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Author(s): Benjamin Galper , Roxana Mehran Added: 3 years ago
Acute coronary syndromes (ACS) result from unstable coronary artery plaques that rupture and can lead to coronary ischaemia, unstable angina and myocardial infarction. The treatment goals in ACS focus on reducing ischaemia, preventing further progression of thrombotic plaque by disturbing the milieu of thrombosis and platelet aggregation taking place within the coronary artery and, in the case of… View more

Anticoagulation

Standards & Guidelines
Author(s): Timm Bauer , Christian Hamm Added: 3 years ago
Introduction Antiplatelet therapy is a cornerstone in coronary artery disease (CAD) management. Acetylsalicyclic acid (ASA) has been known for many decades to have antithrombotic efficacy. Already in the 1980’s, the ISIS-2 study demonstrated that ASA reduces mortality in acute myocardial infarction (AMI) by 23 %.1 ASA leads to irreversible inactivation of cyclooxygenase 1 and thereby blocks the… View more

Anticoagulation
Johanne Silvain
Job title: Prof. Johanne Silvain is professor of medicine at the Pierre and Marie Curie University in Paris, France.
He is an interventional cardiologist, with experience in coronary angioplasty and OTC, and is Director of the Coronary Intensive Care Unit.He is licensed at the University of Medicine of Paris (UPMC) and is the author of over 100 publications in prestigious authoritative journals.The research interests of Dr. Silvain fall within the field of thrombosis (composition of thrombi) and antithrombotic… View more
Author(s): Sri Raveen Kandan , Thomas W Johnson Added: 3 years ago
Antiplatelet Therapy Current guidelines support the early administration of oral antiplatelet agents upstream of angiographic assessment and intervention.1 Aspirin is commonly given by the first medical contact and additional oral antiplatelet drugs are administered on arrival in hospital (see Figure 1). Aspirin The efficacy of aspirin in acute ST-segment elevation myocardial infarction (STEMI)… View more

Anticoagulation
Robert F Storey
Job title: Professor and Honorary Consultant in Cardiology
Prof Robert Storey is Academic Director and an honorary Consultant Cardiologist for the Cardiology and Cardiothoracic Surgery Directorate, Sheffield Teaching Hospitals NHS Foundation Trust. He is Professor of Cardiology at the University of Sheffield, UK, where he has headed a platelet research group since 2002 within the Department of Cardiovascular Science. He has a special interest in the… View more
Foreword

Article

Author(s): Simon Kennon Added: 3 years ago
This year’s third and final issue of Interventional Cardiology Review includes an excellent series of papers on chronic total occlusions. Over the last 10 years, particularly the last 5 years, this area has been transformed by the introduction of new technologies and new techniques. Cases which would only have been considered for surgical revascularisation a decade ago are now routinely being… View more

Intervention
Foreword

Article

Author(s): Simon Kennon Added: 3 years ago
The key aim of this journal is to provide up to date and detailed review of data relating to problems commonly encountered by cardiologists. This issue of Interventional Cardiology Review deals with a wide spectrum of such problems. There are four articles that relate to our concerns about thrombus and bleeding in the context of coronary intervention. The effect of bleeding on outcomes following… View more

Vascular Disease and Surgery

Intervention
Foreword

Article

Author(s): Simon Kennon Added: 3 years ago
This year’s two major European interventional cardiology conferences have highlighted the different stages of development of three different aspects of interventional cardiology. Coronary intervention is a mature subspeciality and presentations at the EuroPCR meeting (Paris, 17–20 May 2016) focussed on highly complex (chronic total occlusions) and high-risk (ST-elevation myocardial infarction)… View more

MI/ACS
Author(s): Jean-Pierre Bassand Added: 3 years ago
Anticoagulants and antiplatelet therapies, and revascularisation/ reperfusion with percutaneous coronary interventions (PCIs) or surgery are the mainstay of modern treatment of acute coronary syndromes (ACS) with and without ST-segment elevation. In addition, depending on the clinical presentation, thrombolytic therapy may be necessary in patients with ST-elevation myocardial infarction (MI) who… View more

Anticoagulation

MI/ACS