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Author(s): On Topaz , Allyne Topaz , Pritam R Polkampally Added: 3 years ago
Plaque rupture and subsequent thrombus formation account for most acute myocardial infarctions (AMIs). Percutaneous coronary intervention (PCI) is considered the preferred treatment for ST-segment-elevation myocardial infarction (STEMI), for evolving non-STEMI (NSTEMI) and for rescue intervention post-thrombolytics.1 The main goals of primary and rescue PCI in AMI include restoration of a normal… View more
Author(s): Catalin Toma Added: 1 year ago
TCT 22 - Dr Catalin Toma (University of Pittsburgh Medical Center, Pittsburgh, PA, US) joins us to discuss the findings of the FLASH Study, a real-world registry with over 1300 participants. This trial aims to analyse the safety and effectiveness of Inari's FlowTriever System for the removal of emboli from the pulmonary arteries in patients with acute pulmonary embolism. Dr Toma presents the… View more
Author(s): Krishnaraj S Rathod , Stephen M Hamshere , Tawfiq R Choudhury , et al Added: 3 years ago
Primary percutaneous coronary intervention (PPCI) is the optimal treatment strategy for restoring coronary blood flow in the infarct related artery (IRA) and salvaging myocardium in patients with ST elevation myocardial infarction (STEMI).1,2 Despite this, PPCI fails to restore optimal myocardial perfusion in up to 40 % of patients despite restoring epicardial artery patency as evidenced by… View more
Author(s): Martin G Radvany Added: 3 years ago
Catheter-based vascular interventions continue to evolve as new devices continue to expand the capabilities of interventionalists and improve patient safety. The importance of athero-embolisation during vascular intervention has long been recognised.1 Embolic protection devices (EPDs) were developed to help prevent embolisation during endovascular procedures. The risk of distal embolisation is… View more
Author(s): William R Colyer Jr , Christopher J Cooper Added: 3 years ago
Atherosclerotic renal artery stentosis (RAS) is a frequently recognised cause of secondary hypertension and chronic kidney disease.1–4 Revascularisation of RAS with angioplasty and stenting is often performed with the goals of improved blood pressure control and preserving or improving renal function.5 However, renal artery stenting is sometimes associated with acute worsening of renal function.6… View more
Author(s): Fizzah A Choudry , Roshan P Weerackody , Daniel A Jones , et al Added: 3 years ago
Over the last few decades, primary percutaneous coronary intervention (PCI) has revolutionised the treatment of ST-elevation myocardial infarction (STEMI) with rapid recanalisation of the infarct-related epicardial vessel, resulting in smaller infarct size and a substantial reduction in adverse clinical endpoints.1,2 However, suboptimal myocardial reperfusion is documented to occur in a… View more
Author(s): Phyo Htet Khaing , G Louise Buchanan , Vijay Kunadian Added: 3 years ago
Many profound physiological changes take place in the cardiovascular system during pregnancy to meet the increased metabolic demands of both the mother and foetus. Such changes include an increase in circulating blood volume and cardiac output and decreases in systemic vascular resistance, blood pressure and hypercoagulation.1,2 The increase in circulatory burden during pregnancy and the… View more
Author(s): Michael Haude Added: 3 years ago
Myocardial infarction (MI) is the leading cause of death worldwide in both men and women.1 An impending infarction is recognised by ST elevation, which is predominantly the result of an occlusive thrombosis in a coronary artery. An immediate goal in MI is to restore blood flow through the occluded coronary artery. Reperfusion is carried out using primary percutaneous coronary intervention (PCI)… View more
Author(s): Michael Tsang , Sanjit Jolly Added: 3 years ago
Many advances have been made in the management of ST elevation myocardial infarction (STEMI) over the past three decades.1 This is owed to insight into role that thrombus has in the obstruction of the infarct-related artery (IRA) and the subsequent cascade of the myocardial ischaemia, cell oedema and myocardial necrosis. The institution of reperfusion therapy has revolutionised the care of… View more