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Author(s): Viktor Kočka , Petr Widimsky Added: 3 years ago
Terminology When the first-in-human implantation of a bioresorbable device into the coronary artery was reported in 2007, the term ‘fully bioabsorbable stent’ was used.1 Later, in 2011, Onuma and colleagues explained that the term ‘bioresorbable’ provides a more precise description of the complete cleavage of macromolecules to small molecules with total elimination and the term ‘scaffold’ was… View more
Research Area(s) / Expertise:

Peripheral Artery Disease - General

Job title: Associate Professor of Vascular Surgery
Professor Varcoe is a vascular surgeon at Sydney’s Prince of Wales Hospitals where he is director of the operating theatres and of the Vascular Institute, one of Australia’s most prestigious clinical trials centres. His clinical practice specialises in the minimally invasive treatment of aortic conditions, carotid disease and the full gamut of occlusive arterial disease of the lower limb for… View more
Author(s): Nienke S van Ditzhuijzen , Jurgen M Ligthart , Nico Bruining , et al Added: 3 years ago
The indications for percutaneous coronary intervention (PCI) have expanded steadily during the past years. After the days of the revascularisation of obstructive coronary artery disease (CAD) by balloon angioplasty,1 the introduction of coronary stents has essentially contributed to PCI being one of the most frequently performed invasive therapeutic procedures worldwide. Bare metal stents (BMS)… View more
Author(s): Sidakpal Panaich , Theodore Schreiber , Cindy Grines Added: 3 years ago
Percutaneous coronary intervention (PCI) is one of the most commonly performed procedures in cardiology. More recently, the limitations of rigid metallic stents have led to the development of bioresorbable scaffolds (BRS). The earliest version of bioresorbable stent developed and tested in humans in 1990 was the Igaki-Tamai stent. It featured a thermal and balloon expandable stent that showed… View more
Author(s): Robin P Kraak , Maik J Grundeken , Robbert J de Winter , et al Added: 3 years ago
In the past three decades, significant progress has been made in the treatment of coronary artery disease. From the introduction of balloon angioplasty by Andreas Grüntzig in 19771 to metallic drugeluting stents with thin stent struts coated with cytotoxic or cytostatic drugs,2,3 with biocompatible/biodegradable polymers,4 with or without endothelial progenitor cell-capturing technology.5 However… View more
Author(s): Roberto Diletti , Nicolas M Van Mieghem Added: 3 years ago
Since Andreas Gruentzig presented his pioneering work in 1977, 'three revolutions' in percutaneous coronary interventions (PCI) have characterised the field of interventional cardiology. Plain old balloon angioplasty (POBA) was refined by the introduction of bare metal stenting (BMS) (second revolution) to address the issue of acute vessel recoil and unacceptably high rates of restenosis. Drug… View more
Author(s): David Power Added: 1 month ago
CRT 24 - We are joined in this short virtual interview by investigator, Dr David Power (Mount Sinai Hospital, US) to discuss the latest findings from the ABSORB trial series, revealed in 2024 at the CRT conference.ABSORB III is a prospective, randomized, single-blind, multicenter trail aiming to support the pre-market approval of the Absorb bioresorbable vascular scaffold (Abbott) for the… View more
Author(s): Axel Schmermund , Holger Eggebrecht Added: 3 years ago
It is estimated that 15-20 % of all coronary interventional procedures involve side branches.1 Side branches are frequently related to periprocedural complications. Side branch occlusion or compromise appears to be the underlying cause of approximately 30 % of periprocedural myocardial infarctions.2 Periprocedural infarction in turn is an important predictor of midterm mortality3. Considering any… View more
Author(s): Rebecca L Noad , Colm Hanratty , Simon J Walsh Added: 3 years ago
As the role of percutaneous coronary intervention (PCI) has evolved, inevitably, so too has the technology associated with this specialty. Initially, plain old balloon angioplasty (POBA) was developed as a strategy to ‘stretch’ focal stenoses within the coronary arteries leading to a relief from ischaemia and angina. Whilst potentially of great benefit to some patients, POBA was beset by a series… View more