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PROMOTED
Author(s):
Nicolas M Van Mieghem
,
Kendra J Grubb
,
David Hildick-Smith
,
et al
Start date:
Mar 26, 2024
Author(s):
Yves Louvard
,
Marie-Claude Morice
,
Thomas Hovasse
,
et al
Added:
3 years ago
Due to anatomical reasons and the distributive function of the coronary tree, bifurcation sites are prone to the development of atherosclerotic lesions as a result of flow turbulence generating pro-atherogenous low wall shear stress (WSS). Over the past few years, coronary bifurcation lesions have been the subject of intense therapeutic discussions fuelled by new definitions, classifications …
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Author(s):
Angela Hoye
,
Scot Garg
Added:
3 years ago
Coronary artery bifurcations are at an increased risk of the development of coronary atherosclerosis because of turbulent flow and low shear stress. Bifurcation lesions account for between 8% and 22% of all percutaneous coronary interventions (PCI) and have long posed a problem for interventional cardiologists.
Published data show bifurcation lesions treated using bare metal stents (BMS) have…
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Author(s):
Binita Shah
Added:
4 years ago
Dr Binita Shah (NYU Langone Health, New York, NY, US) discusses Colchicine in Percutaneous Coronary Intervention (PCI).
Questions:
1.What is colchicine and why study it in PCI?
2.What was the study design, patient population and primary and secondary outcomes?
3.What were your outcomes?
4.How do these compare to those in the COLCOT study?
5.How should your study be interpreted in clinical…
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Author(s):
Luca Longobardo
,
Alessio Mattesini
,
Serafina Valente
,
et al
Added:
3 years ago
Coronary artery bifurcation lesions are treated in 15–20% of percutaneous coronary intervention (PCI) procedures and are still plagued by worse outcomes.1 This is in spite of recent significant advancements in stent technology in general and in bifurcation stenting techniques in particular. Conventional angiography provides only limited information about bifurcation anatomy, plaque distribution…
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Author(s):
Gregory J Dehmer
Added:
3 years ago
The use of percutaneous coronary intervention (PCI) for coronary artery revascularization has grown considerably since the first balloon angioplasty in 1977. Improvements in equipment and drug therapies plus the development of coronary artery stents have all contributed to the growth of PCI as an alternative to surgical revascularization. Compared with the early days of balloon angioplasty, when…
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Author(s):
Eric W Holroyd
,
Chee W Khoo
,
Rob Butler
,
et al
Added:
3 years ago
Major bleeding or haemorrhage following a percutaneous coronary intervention (PCI) is not a benign event. There is now convincing evidence that it independently predicts increased mortality and adverse outcomes in patients.1,2 The adverse outcomes associated with a bleeding event are not just as a direct result of the haemorrhagic event, such as whether or not a patient survives their…
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Author(s):
Benjamin Galper
,
Roxana Mehran
Added:
3 years ago
Acute coronary syndromes (ACS) result from unstable coronary artery plaques that rupture and can lead to coronary ischaemia, unstable angina and myocardial infarction. The treatment goals in ACS focus on reducing ischaemia, preventing further progression of thrombotic plaque by disturbing the milieu of thrombosis and platelet aggregation taking place within the coronary artery and, in the case of…
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Author(s):
Kristina Grønborg Laut
,
Alma Becic Pedersen
,
Timothy L Lash
,
et al
Added:
3 years ago
Coronary heart disease (CHD) remains a leading cause of mortality and disability for both men and women in Europe, accounting for 1.92 million deaths each year.1 One in five women (22%) and one in five men (21%) die from the disease.1 This significant burden necessitates ongoing improvements in patient management and treatment, to minimise the impact of cardiovascular conditions on both patients…
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Author(s):
Rajiv Rampat
,
David Hildick-Smith
Added:
3 years ago
Left main stem (LMS) disease is identified in up to 5 % of diagnostic angiography cases.1 It has major prognostic significance due to the proportion of myocardium at risk. Many years ago, the Coronary Artery Surgery Study (CASS) registry demonstrated the superiority of coronary artery bypass grafting (CABG) over medical therapy with a 5-year mortality reduction from 43 % to 16 % in symptomatic…
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