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Percutaneous Closure of Patent Foramen Ovale
Author(s): Stefan Stortecky , Stephan Windecker Added: 3 years ago
Cerebrovascular events are associated with high rates of morbidity and mortality and are considered the global second leading cause of death.1 The majority of strokes are ischemic, although the etiology remains unknown in a considerable number of patients,2 commonly referred to as “non-defined” or “cryptogenic.”3 Data from epidemiologic studies point towards a relevant association between the… View more

Standards & Guidelines

Prevention & Chronic Conditions
Author(s): Antonio L Bartorelli , Claudio Tondo Added: 3 years ago
On average, every 20 seconds someone in the US1 or in Europe2 has a stroke. This adds up to a total of about 1.7 million strokes per year in these two continents, affecting about 0.22% of the population each year. In the US alone, every four minutes someone dies from stroke, yielding a total mortality of about 140,000 deaths per year. As a result, stroke is the world’s third leading cause of… View more

Prevention & Chronic Conditions
Author(s): Joelle Kefer Added: 3 years ago
Atrial septal abnormalities are common congenital lesions remaining asymptomatic until adulthood in a great number of patients. The most frequent atrial septal defects in adults are ostium secundum atrial septal defect (ASD) and patent foramen ovale (PFO), both approachable by transcatheter closure using device implantation. The first non-surgical ASD closure was performed in 1975 by Mills and… View more

Vascular Disease and Surgery

Intervention
Author(s): Raquel del Valle-Fernández , Carlos E Ruiz Added: 3 years ago
The foramen ovale provides communication between both atria in utero, and although anatomical closure usually occurs in the first two years of life, it may remain patent (patent foramen ovale [PFO]) into adulthood. The autopsy prevalence of PFO was 27% among 965 otherwise normal hearts,1 and transoesophageal echocardiography detected PFO in 24.3% of 585 randomly sampled individuals.2 PFO is… View more

Intervention

Heterogeneous Populations
Patent Foramen Ovale Closure: State of the Art
Author(s): Joel P Giblett , Lynne K Williams , Stephen Kyranis , et al Added: 3 years ago
Patent foramen ovale (PFO) is common and occurs in 20–34% of the population.1 In most infants, the foramen ovale closes soon after birth, with a reduction in pulmonary vascular resistance raising the left atrial pressure above that of the right atrium during the first few breaths, closing the septum. In a significant proportion of individuals, the primum and secundum atrial septa do not fuse, and… View more

Prevention & Chronic Conditions
Patent Foramen Ovale Closure in 2019
Author(s): Joel P Giblett , Omar Abdul-Samad , Leonard M Shapiro , et al Added: 3 years ago
Patent foramen ovale (PFO) is a common abnormality, occurring in 20–34% of the population.1 In the majority of infants, closure of the foramen ovale occurs soon after birth, as negative intrathoracic pressure associated with the first breaths closes the PFO. In some cases, the primum and secundum atrial septa fail to fuse and closure remains incomplete. There is continuing communication between… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Research Area(s) / Expertise:

Inherited and Congenital Cardiac Conditions
Professor Lars Søndergaard is a consultant cardiologist at Rigshospitalet – Copenhagen, Denmark. Professor of Cardiology at University of Copenhagen, he published over 300 peer reviewed articles, and more than 15 textbook chapters. His research interests are focused on adults with congenital heart diseases and catheter-based heart valve interventions, as well as congenital and structural heart… View more
Carlos Morillo
Prof Carlos Morillo is a cardiac electrophysiologist, currently serving in the Chief Division of Cardiology at theLibin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada. Prof Morillo has extensively researched Chagas disease since 1990, and was involved in the initial studies related to autonomic control in the different stages of the disease and the use of beta… View more
Author(s): Amit Bhan , Brian Clapp Added: 3 years ago
The foramen ovale is an integral component of the fetal circulation, responsible for facilitating the flow of placental pre-xygenated venous blood from the right atrium to the left, thereby circumventing the quiescent developing lungs. Physiological closure is usually achieved after birth when pulmonary vascular resistance and right heart pressures reduce, resulting in the left atrial pressure… View more

Vascular Disease and Surgery

Standards & Guidelines
Technological Iteration in TAVI: A live case session
Author(s): Lars Søndergaard , Pablo Lamelas , Won Keun-Kim , et al Start date: Nov 12, 2020

Intervention