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Author(s): John Rawlins , James Wilkinson , Nick Curzen Added: 3 years ago
A chronic total occlusion (CTO) in a coronary artery is defined as “the presence of TIMI 0 flow within an occluded arterial segment of greater than three months standing.”1 The successful percutaneous revascularisation of CTO vessels represents one of the dominant remaining technical challenges in interventional cardiology. CTOs are common, found in between 20 %2 and 50 %3 of all patients with… View more
Research Area(s) / Expertise: Job title: Consultant Interventional Cardiologist
John Rawlins is a Consultant Interventional Cardiologist with a specialist interest in complex coronary and transcatheter valve intervention at University Hospital Southampton (UHS) NHS Trust, having been appointed in 2016. He currently leads the TAVI team at UHS.He qualified from Imperial College School of Medicine in 2003, having completed a BSc in Physiology at University College London in… View more
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Author(s): Simon Kennon Added: 3 years ago
This year’s third and final issue of Interventional Cardiology Review includes an excellent series of papers on chronic total occlusions. Over the last 10 years, particularly the last 5 years, this area has been transformed by the introduction of new technologies and new techniques. Cases which would only have been considered for surgical revascularisation a decade ago are now routinely being… View more
Author(s): Enoch Akowuah Added: 1 year ago
ACC.23/WCC—DrEnoch Akowuah (James Cook University Hospital, UK) joins us to share the findings of the UK Mini-Mitral trial (National Institute of Health Research). This study is a multicentre, expertise-based randomised controlled trial that aimed to compare the safety and effectiveness of a minimally-invasive thoracotomy compared to conventional sternotomy in treating patients with degenerative… View more
Author(s): J Raider Estrada , Jonathan D Paul , Atman P Shah , et al Added: 3 years ago
While the breadth of procedural offerings in interventional cardiology (IC) has exponentially expanded over the past four decades to include cardiac structural, peripheral arterial, and venous interventions, percutaneous coronary intervention (PCI) remains at the core of the field, accounting for the greatest percentage of therapeutic catheter-based procedures performed by IC practitioners in the… View more
Author(s): Alfredo Galassi , Aaron Grantham , David Kandzari , et al Added: 3 years ago
Section A Techniques for Chronic Total Occlusions Revascularisation Access Route, Guiding Catheter Selection and Contralateral Injection The femoral approach is the preferred access route by most operators. However, the radial approach might be chosen because of severe peripheral vascular disease, operator’s preference or for contralateral injection. The guiding principle of access selection is… View more
Author(s): Matthias Brunn , Isabelle Durand-Zaleski Added: 3 years ago
A Primer on Health Economics The objective of this technical paper is to provide a user-friendly primer on economic evaluation applied to aortic valve replacement. We will firstly present the general concepts of economic evaluation with a specific focus on the reasons why the results of academic research may not be relevant to the physicians in charge of managing a department or to hospital… View more
Author(s): Corrado Tamburino , Davide Capodanno Added: 3 years ago
Recently, many eminent scientific journals have published long-term follow-up data from both randomised clinical trials (RCTs) and registries of patients treated with percutaneous coronary intervention (PCI) undergoing drug-eluting stent (DES) implantation. In fact, this is the only course of action to address the concerns regarding DES safety that were first raised almost two years ago.1… View more
Author(s): Robert A Byrne , Shmuel Banai , Roisin Colleran , et al Added: 3 years ago
Newer generation polymeric metallic drug-eluting stents (DES) have shown improved efficacy and safety compared with bare-metal stents and first-generation DES, improving patient outcomes after percutaneous coronary intervention (PCI) and facilitating the treatment of more complex coronary disease.1 However, clinical outcomes in certain lesion and patient subsets remain suboptimal. Procedural and… View more