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PROMOTED
Author(s):
Nicolas M Van Mieghem
,
Kendra J Grubb
,
David Hildick-Smith
,
et al
Start date:
Mar 26, 2024
Author(s):
Mirvat Alasnag
,
Lina Yaqoub
,
Ammar Saati
,
et al
Added:
3 years ago
Historical Perspective and Early Experience
Historically, coronary artery bypass grafting (CABG) surgery has been the gold standard treatment for left main coronary artery (LMCA) disease. However, with the developments and advancements in the interventional cardiology field, percutaneous coronary intervention (PCI) has become a safe alternative management option to CABG in select patients. Today…
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Author(s):
Alfonso Ielasi
,
Alaide Chieffo
Added:
3 years ago
A critical stenosis in left main coronary artery (LMCA) is observed in 3–5% of all patients who undergo coronary angiography and in 10–30% of patients who undergo coronary artery bypass grafting (CABG).1 Significant LMCA disease is a high-risk condition because of the extent of jeopardised myocardium.
Current practice guidelines recommend CABG as the standard therapy for patients with…
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Author(s):
Samir R Kapadia
,
Stephen G Ellis
,
Nyal Borges
Added:
3 years ago
Obstructive unprotected left main coronary artery (ULMCA) disease has been recognised as a high-risk condition since the 1960s owing to the large quantum of myocardium supplied by this system (see Figure 1). In that era, medical therapy was the only available management and 5-year mortality rates exceeded 60 %.1 With the introduction of coronary artery bypass grafting (CABG) it became clear that…
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Author(s):
Giovanni Luigi De Maria
,
Adrian P Banning
Added:
3 years ago
Detection of obstructive disease of the left main coronary artery (LMCA) is relatively unusual in the catheterisation laboratory, as it accounts for approximately 4 % of all coronary angiograms, with isolated LMCA disease observed in only 5–10 % of these cases.1
Intervention to the LMCA is, however, notable compared to the treatment of coronary stenosis elsewhere in the coronary tree. First,…
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Author(s):
Prakriti Gaba
Added:
1 year ago
CRT 23 - In this short video, Dr Prakriti Gaba (Brigham and Women's Hospital, US) joins us to discuss the late-breaking data from a pooled analysis of four trials comparing coronary artery bypass graft (CABG) with percutaneous coronary intervention (PCI) in patients with left main disease: SYNTAX, PRECOMBAT, NOBLE and EXCEL. In this study, individualised patient data were pooled and categorised…
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Author(s):
Jonathan Xinguo Fang
,
Arthur Sze-Yue Yung
,
Simon Cheung-Chi Lam
,
et al
Added:
1 year ago
Author(s):
Oluseun Alli
,
David Holmes Jr
Added:
3 years ago
Abstract
Patients with complex and multivessel disease present challenging clinical problems in defining treatment strategies. The Synergy between PCI with taxus and cardiac surgery (SYNTAX) trial, which included both a randomised as well as a registry experience has clarified many issues. These include the extent and severity of the disease, the clinical presentation, and the metrics used for…
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Author(s):
Rajiv Rampat
,
David Hildick-Smith
Added:
3 years ago
Left main stem (LMS) disease is identified in up to 5 % of diagnostic angiography cases.1 It has major prognostic significance due to the proportion of myocardium at risk. Many years ago, the Coronary Artery Surgery Study (CASS) registry demonstrated the superiority of coronary artery bypass grafting (CABG) over medical therapy with a 5-year mortality reduction from 43 % to 16 % in symptomatic…
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