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Author(s): Joel P Giblett , Omar Abdul-Samad , Leonard M Shapiro , et al Added: 3 years ago
Patent foramen ovale (PFO) is a common abnormality, occurring in 20–34% of the population.1 In the majority of infants, closure of the foramen ovale occurs soon after birth, as negative intrathoracic pressure associated with the first breaths closes the PFO. In some cases, the primum and secundum atrial septa fail to fuse and closure remains incomplete. There is continuing communication between… View more
Author(s): Joel P Giblett , Lynne K Williams , Stephen Kyranis , et al Added: 3 years ago
Patent foramen ovale (PFO) is common and occurs in 20–34% of the population.1 In most infants, the foramen ovale closes soon after birth, with a reduction in pulmonary vascular resistance raising the left atrial pressure above that of the right atrium during the first few breaths, closing the septum. In a significant proportion of individuals, the primum and secundum atrial septa do not fuse, and… View more
Author(s): Phyo Htet Khaing , G Louise Buchanan , Vijay Kunadian Added: 3 years ago
Many profound physiological changes take place in the cardiovascular system during pregnancy to meet the increased metabolic demands of both the mother and foetus. Such changes include an increase in circulating blood volume and cardiac output and decreases in systemic vascular resistance, blood pressure and hypercoagulation.1,2 The increase in circulatory burden during pregnancy and the… View more
Author(s): Antonio L Bartorelli , Claudio Tondo Added: 3 years ago
On average, every 20 seconds someone in the US1 or in Europe2 has a stroke. This adds up to a total of about 1.7 million strokes per year in these two continents, affecting about 0.22% of the population each year. In the US alone, every four minutes someone dies from stroke, yielding a total mortality of about 140,000 deaths per year. As a result, stroke is the world’s third leading cause of… View more
Job title: Interventional Cardiologist
Personal History Born and raised in Maple Plain, MN, Dr Jason Bartos is a Cardiologist and Assistant Professor of Medicine at the University of Minnesota. He is also the Associate Medical Director of the Center for Resuscitation Medicine and the President of the Minnesota Mobile Resuscitation Consortium (MMRC), where he works to improve the survival rates of cardiac arrest.4 Academic… View more
Author(s): Stefan Stortecky , Stephan Windecker Added: 3 years ago
Cerebrovascular events are associated with high rates of morbidity and mortality and are considered the global second leading cause of death.1 The majority of strokes are ischemic, although the etiology remains unknown in a considerable number of patients,2 commonly referred to as “non-defined” or “cryptogenic.”3 Data from epidemiologic studies point towards a relevant association between the… View more
Author(s): Joelle Kefer Added: 3 years ago
Atrial septal abnormalities are common congenital lesions remaining asymptomatic until adulthood in a great number of patients. The most frequent atrial septal defects in adults are ostium secundum atrial septal defect (ASD) and patent foramen ovale (PFO), both approachable by transcatheter closure using device implantation. The first non-surgical ASD closure was performed in 1975 by Mills and… View more
Author(s): Raquel del Valle-Fernández , Carlos E Ruiz Added: 3 years ago
The foramen ovale provides communication between both atria in utero, and although anatomical closure usually occurs in the first two years of life, it may remain patent (patent foramen ovale [PFO]) into adulthood. The autopsy prevalence of PFO was 27% among 965 otherwise normal hearts,1 and transoesophageal echocardiography detected PFO in 24.3% of 585 randomly sampled individuals.2 PFO is… View more