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Distinguished Lecture: Heart Recovery – Insights from RESTAGE-HF
Author(s): Emma Birks Added: 1 year ago

Heart Failure
Author(s): Bruce R Brodie Added: 3 years ago
Abstract This article reviews optimum therapies for the management of ST-elevation myocardial infarction (STEMI) with primary percutaneous coronary intervention (PCI). Optimum anti-thrombotic therapy includes aspirin, bivalirudin and the new anti-platelet agents prasugrel or ticagrelor. Stent thrombosis (ST) has been a major concern but can be reduced by achieving optimal stent deployment, use… View more

Vascular Disease and Surgery

Prevention & Chronic Conditions
Author(s): Subbarao Myla , Sepideh Kazemi Added: 3 years ago
Insights from Carotid Artery Stenting Registries Registries tend to have less stringent inclusion and exclusion criteria than randomised trials and provide real-world data on a broad variety of patients treated by a range of interventionists of varying experience. Registries serve to provide first-time evaluation of new devices, help set up learning curve pearls, can be hypothesis-generating and… View more

Vascular Disease and Surgery

Imaging & Diagnostics
Acute MI to Heart Failure: the Past, the Present and the Future
Author(s): Eugene Braunwald Added: 6 years ago

Heart Failure

MI/ACS
Author(s): Jason N Katz , Sunil V Rao Added: 3 years ago
There has been a significant evolution in the management of patients with acute coronary syndromes (ACS), largely driven by advances in pharmacological therapy. Increased implementation of evidence-based antithrombotics and antiplatelet agents has led to improved patient outcomes.1,2 Additionally, management algorithms favouring early invasive intervention in high-risk patients are gaining… View more

Anticoagulation

Imaging & Diagnostics
How to Diagnose and Manage Angina Without Obstructive CAD
Author(s): Tom Ford , Colin Berry Added: 3 years ago
Ischaemic heart disease persists as the leading global cause of death and lost life years in adults.1 Angina is a common clinical presentation of ischaemic heart disease related to a supply:demand mismatch of myocardial blood flow, typically provoked by exertion or stress. Invasive coronary angiography is the reference test for angina and identifies obstructive coronary artery disease (CAD) as a… View more

Prevention & Chronic Conditions
Author(s): Constantinos O’Mahony , Saidi Mohiddin , Charles Knight Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a genetic disorder of cardiac muscle with a heterogeneous clinical course.1 The disease is clinically characterised by left ventricular hypertrophy (LVH), which is typically asymmetric, and a subgroup of patients have left ventricular outflow tract obstruction (LVOTO) caused by systolic anterior motion (SAM) of the mitral valve leaflet(s).2,3 LVOTO is often… View more

Heterogeneous Populations

Heart Failure
Management of Acute Coronary Syndromes During the Coronavirus Disease 2019 Pandemic: Deviations from Guidelines and Pragmatic Considerations for Patients and Healthcare Workers
Author(s): Henry Seligman , Sayan Sen , Sukhjinder Nijjer , et al Added: 3 years ago
International guidelines provide clinicians with evidence-based recommendations on how to manage patients presenting with acute coronary syndromes (ACS). Guidance includes the appropriateness and optimal timing for percutaneous interventions as well as the ideal length of hospital stay.1–5 However, the current global pandemic of coronavirus disease 2019 (COVID-19), has posed an unprecedented… View more

COVID-19
Author(s): Dagmar M Ouweneel , Bimmer E Claessen , Krischan D Sjauw , et al Added: 3 years ago
The main goal of mechanical cardiac assistance is to provide haemodynamic support in case of an endangered coronary or systemic circulation by increasing or maintaining coronary and systemic blood flow. In addition to haemodynamic support, mechanical cardiac assistance may also provide myocardial protection by unloading the ventricle. The experience with percutaneous mechanical support devices is… View more

Standards & Guidelines

MI/ACS