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Author(s): Andrea Pacchioni , Dimitris Nikas , Carlo Penzo , et al Added: 3 years ago
Transcatheter aortic valve implantation (TAVI) and endovascular aortic repair (EVAR) are increasingly being used as therapeutic options for patients with severe aortic stenosis ineligible for surgery and with aortic aneurysm with suitable anatomical features. Despite encouraging results from randomised studies and registries regarding the pursuit of endovascular treatment in selected patients,… View more
Author(s): Stephane Noble , Marco Roffi Added: 3 years ago
Since the first human transcatheter aortic valve implantation (TAVI)performed through an antegrade transfemoral approach (i.e. femoral venous access, transseptal puncture advancement of the device to the left ventricle and antegradely through the aortic valve), the venous approach has been abandoned and different arterial access routes such as the transfemoral, transapical, subclavian or direct… View more
Author(s): Maarten P van Wiechen , Jurgen M Ligthart , Nicolas M Van Mieghem Added: 3 years ago
Minimally invasive procedures such as endovascular aneurysm repair (EVAR), transcatheter aortic valve implantation (TAVI) and implantation of mechanical circulatory support (MCS) are gaining ground on traditional surgery.1–3 These procedures require large-bore access, which is inherently associated with vascular complications and bleeding. Despite the reduction in size of these devices (Table 1),… View more
Author(s): Benjamin H Holland , Robert J Applegate Added: 3 years ago
Abstract Femoral access remains a vital route for many cardiac and non-cardiac procedures, including those involving the use of large delivery systems. In the common femoral artery access is extremely important to minimise complications and optimise use of closure devices. Dissatisfaction with haemostasis achieved by manual compression stimulated development of VCDs that provide quick and… View more
Author(s): Mohamed Abdel-Wahab Added: 2 years ago
In this short summary interview, Dr Mohamed Abdel-Wahab (Heart Center Leipzig, University of Leipzig, DE) talks about the findings of the CHOICE-CLOSURE trial. The randomized trial investigated the plug-based versus suture-based large-bore vascular closure. Discussion points: 1. Importance of this study 2. Study design and patient cohort 3. Key findings 4. Impact on practice 5. Next steps … View more
Author(s): Amar Krishnaswamy , Emin Murat Tuzcu , Samir R Kapadia Added: 3 years ago
Among patients undergoing surgical valve replacement, 1–5 % of patients with an aortic valve replacement (AVR) and 2–12 % with a mitral valve replacement (MVR) may develop paravalvular regurgitation or ‘leak’ (PVL).1–3 In the era of transcatheter aortic valve replacement (TAVR) with first-generation balloon expandable valves, up to 17 % of patients may be left with moderate or severe PVL, also… View more
Author(s): Benjamin H Holland , Robert J Applegate Added: 3 years ago
Manual compression has been the gold standard for obtaining haemostasis at the femoral artery access site since being introduced in conjunction with the Seldinger technique in the 1950s.1 However, the limitations of manual compression, including patient discomfort, delayed haemostasis and ambulation and bleeding at the access site despite satisfactory initial haemostasis, have spurred the… View more
Author(s): Angela Hoye Added: 3 years ago
The coronary tree is comprised of arteries which divide into ever smaller branches to supply the myocardium. This means that the diameter of the vessel proximal to a bifurcation is always larger than the diameter of the main vessel distal to the bifurcation. The proximal optimisation technique (POT) was proposed by Dr Olivier Darremont as a technique to compensate for this difference in diameters… View more
Author(s): Kendra J Grubb Added: 1 year ago
Dr Kendra Grubb (Emory Structural Heart and Valve Center, GA, US) outlines the interim analysis of the Optimize PRO Study (NCT04091048), originally presented at EuroPCR 2022. Optimize PRO aimed to evaluate valve performance and procedural outcomes of optimised TAVR care using Medtronic's Evolut™ PRO and Evolut™ PRO+ devices. Findings are promising and show that no patients experienced a… View more