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Author(s): Christian Homsy Added: 3 years ago
Cardiovascular disease (CVD) is the largest cause of mortality in the world, before cancer and infectious diseases. World Health Organization statistics for 2008 show that close to one in three deaths (29 %) in the world is due to CVD, representing more than 17 million per year. Cardiac diseases represent around 60 % of CVDs and are the single largest cause of death in the CVD population. Cardiac… View more

Vascular Disease and Surgery

Heart Failure
Author(s): Alexandre Abizaid Added: 3 years ago
In treating thrombus-loaded lesions through percutaneous coronary intervention (PCI) in the settings of acute myocardial infarction (MI), saphenous vein grafts (SVGs) and acute coronary syndromes (ACS), distal embolisation is a recognised prevalent occurrence, adversely affecting reperfusion and mortality rates. Thus, efficient management of embolisation, in terms of both reduced occurrence and… View more

MI/ACS

Intervention
Author(s): Giancarlo Marenzi , Antonio L Bartorelli Added: 3 years ago
Primary angioplasty represents the best available strategy for treatment of ST-segment elevation myocardial infarction (STEMI).1 However, its application in patients with chronic kidney disease is particularly problematic and not well characterised. One of the main reasons for this is that such patients have typically been excluded from clinical trials evaluating the outcome of coronary… View more

Imaging & Diagnostics

MI/ACS
Management of Acute Coronary Syndromes During the Coronavirus Disease 2019 Pandemic: Deviations from Guidelines and Pragmatic Considerations for Patients and Healthcare Workers
Author(s): Henry Seligman , Sayan Sen , Sukhjinder Nijjer , et al Added: 3 years ago
International guidelines provide clinicians with evidence-based recommendations on how to manage patients presenting with acute coronary syndromes (ACS). Guidance includes the appropriateness and optimal timing for percutaneous interventions as well as the ideal length of hospital stay.1–5 However, the current global pandemic of coronavirus disease 2019 (COVID-19), has posed an unprecedented… View more

COVID-19
Sex and Transcatheter Aortic Valve Implantation
Author(s): Alessandra Laricchia , Barbara Bellini , Vittorio Romano , et al Added: 3 years ago
Transcatheter aortic valve implantation (TAVI) is included in guidelines for the treatment of severe symptomatic aortic stenosis (AS) in patients with intermediate to high risk for standard surgical therapy.1 The gender-related difference in the pathophysiology of heart disease (and consequently in its clinical course and treatment) has already been identified as an issue in interventional… View more

Demographic
Evidence-based Management of Cardiogenic Shock After Acute Myocardial Infarction
Author(s): Karl Werdan , Martin Russ , Michael Buerke , et al Added: 3 years ago
Cardiogenic Shock, One of the Unresolved Problems in Cardiology Provided the patient with acute myocardial infarction (AMI) reaches the hospital, he has a more than 90 % probability to survive.1 However, when cardiogenic shock develops, either initially or in the course of the infarction, only one in two patients is alive one year later.2,3 It really seems that all the progress in the treatment… View more

Standards & Guidelines

MI/ACS
Insights into the Molecular Basis of Acute Cardiac Unloading and Cardioprotection
Author(s): Navin K Kapur Added: 6 years ago

MI/ACS
Cardioprotection for Acute MI in Light of the CONDI2/ERIC-PPCI Trial: New Targets Needed
Author(s): Joel P Giblett , Heerajnarain Bulluck Added: 3 years ago
The translation to clinical practice of agents or techniques that protect against the effect of ischaemia–reperfusion (IR) injury remains one of the most challenging areas of research in the field of cardiovascular medicine.1–4 This is particularly the case when IR injury follows revascularisation for acute MI (AMI). The publication of the combined Effect of Remote Ischaemic Conditioning on… View more

MI/ACS

Intervention
Author(s): Mamas A Mamas , Farzin Fath-Ordoubadi Added: 3 years ago
Bifurcation lesions account for 15–20% of all percutaneous coronary intervention (PCI) cases performed, representing about half a million cases annually.1 But PCI treatment for bifurcation coronary disease has historically yielded less satisfactory results than conventional stenting. The procedure is often technically challenging and has been associated with both lower procedural success rates… View more

Prevention & Chronic Conditions
Anticoagulant Therapy for Acute Coronary Syndromes
Author(s): Eunice NC Onwordi , Amr Gamal , Azfar Zaman Added: 3 years ago
Acute coronary syndromes (ACS) are a major cause of morbidity and mortality. Despite the use of optimal medical therapy and revascularisation there remains a significant risk of vascular events. Registry data indicates a persistent risk even in patients who are event free in the first year following ACS, with as many as 1 in 5 patients suffering a vascular event in the subsequent 3 years.1 The… View more

Anticoagulation

Prevention & Chronic Conditions