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Author(s): Lisa Brandon , Faisal Sharif Added: 3 years ago
Resistant hypertension remains a serious clinical burden despite significant advances in cardiology and healthcare. Hypertension is a chronic condition without any available cure, with significant associated morbidity and mortality, and necessitates lifelong use of medications. It is multifactorial in origin, associated with genetics, lifestyle factors and the metabolic syndrome. Resistant… View more
Author(s): Ajay J Kirtane Added: 2 years ago
In this short summary interview, Dr. Ajay Kirtane (Columbia University Medical Center, US) shares the six-month outcomes of a randomized trial of renal denervation (RDN) versus a sham procedure for resistant hypertension. The RADIANCE-TRIO Trial, presented first at TCT 2021, showed that the additional effects of pharmacologic intervention with maintenance of a BP-lowering effect of endovascular… View more
Author(s): Katrina Mountfort Added: 3 years ago
Hypertension is one of the most important public health problems of the 21st century, with a global prevalence of around 30 %.1 In 2010, it accounted for 7.5 million deaths worldwide, representing 12.8 % of the global total.2 Furthermore, its prevalence is projected to rise to 1.5 billion hypertensive patients in 2025.3 Despite the availability of numerous safe and effective antihypertensive… View more
Author(s): Vikas Kapil , Ajay K Jain , Melvin D Lobo Added: 3 years ago
Up to one-in-five treated hypertensive patients are deemed to be treatment resistant1-3 (on at least three different anti-hypertensive medication classes, including a diuretic)4-6 and have high cardiovascular risk.7-9 There is a paucity of high-quality evidence to suggest that the addition of a fourth line (or fifth, sixth line, etc.) medication is likely to bring either hypertension under… View more
Author(s): Dominik Linz , Felix Mahfoud , Sebastian Ewen , et al Added: 3 years ago
The sympathetic nervous system regulates cardiac output, blood pressure (BP), heart rate and volume, electrolyte balance and composition of body fluids. The afferent signals to the brain are regulated by mechanosensitive baroreceptors, volume sensors and chemoreceptors located in the vessels and in many other organs, particularly in the heart, kidney, lung, brain and muscles. Sympathetic nervous… View more
Author(s): Michel Burnier , Roland E Schmieder , , et al Added: 1 year ago
In this on-demand version of the live broadcast, Radcliffe Medical Education brings together a globally-renowned European and American faculty to share best practices on resistant hypertension and renal denervation (RDN). This programme has been carefully curated for healthcare professionals that manage patients with resistant hypertension. This expert guidancewill distil the most… View more
Author(s): Nicolas M Van Mieghem , Joost Daemen Added: 1 year ago
Stay updated on the AHA 22 late-breaking data! In this information packed episode of the View from the Thoraxcenter, hosts Dr Joost Daemen and Prof Nicolas Van Mieghem (Thoraxcenter, Erasmus MC, Rotterdam, NL) analyse the data from 10 late-breaking trials presented at the Scientific Sessions. What are the key take-aways from AHA 22? What are the most promising findings? How should we understand… View more