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Author(s): Phyo Htet Khaing , G Louise Buchanan , Vijay Kunadian Added: 3 years ago
Many profound physiological changes take place in the cardiovascular system during pregnancy to meet the increased metabolic demands of both the mother and foetus. Such changes include an increase in circulating blood volume and cardiac output and decreases in systemic vascular resistance, blood pressure and hypercoagulation.1,2 The increase in circulatory burden during pregnancy and the… View more
Author(s): Gianfranco Aprigliano , Altin Palloshi , Nuccia Morici , et al Added: 3 years ago
Cardiovascular diseases represent the leading cause of mortality in pregnancy.1,2 They are classified as direct (acute onset disease) or indirect (worsening of pre-existing cardiac disease). This overview is focused on acute coronary syndrome (ACS) in pregnancy and the post-partum period. ACS in this setting is a rare condition, but in the last two decades its incidence has grown.3 This… View more
Author(s): Meril Life Sciences Added: 3 years ago
The first-generation drug-eluting stents (DES) initially demonstrated good promise in terms of reducing the degree of restenosis. They succeeded in arresting the neo-intimal proliferation, which was the bane of coronary stents.1 Over a period of time, however, the polymeric degradation by-products failed to bring about an essential component of the healing process: endothelialisation. Failure of… View more
Author(s): Andrejs Erglis , Sanda Jegere , Inga Narbute Added: 3 years ago
Intravascular ultrasound (IVUS) is the first catheter-based imaging modality that has been widely used in interventional cardiology.1 It creates cross-sectional images of the vessel lumen and the arterial wall and provides valuable diagnostic information to angiography regarding lumen and vessel measurements and plaque morphology. This information helps clinical decision-making in ambiguous… View more
Author(s): Giuliano Costa , Enrico Criscione , Denise Todaro , et al Added: 3 years ago
Aortic stenosis (AS) is one of the most common valvular diseases in developed countries and its prevalence is projected to increase over the next decade as the population ages.1,2 Transcatheter aortic valve implantation (TAVI) is an established alternative to surgery for treatment of patients with symptomatic, severe AS.3 As the latest multicentre trials have established the role of TAVI… View more
Author(s): George D Dangas Added: 2 years ago
Dr George Dangas (Mount Sinai Hospital, New York, NY, US) discusses the results of the TWILIGHT-Stent trial, presented at ESC 2021. This study examined the incidence of ischemic and bleeding events in patients treated with contemporary drug-eluting stents over 3-15 months. This trial also examined ticagrelor monotherapy vs ticagrelor with aspirin. Questions: 1. What were the main aims of… View more