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Author(s): Gary M Ansel , Peter A Schneider Added: 3 years ago
Clinical Infrapopliteal Disease Critical limb ischaemia (CLI) typically presents as rest pain, tissue ulceration or frank tissue loss with gangrene, often accompanied by infection. Occasionally a patient may also present with claudication that is so severe that the patient is restricted to a few feet of ambulation. These patients sometimes have early rest pain on further questioning. Diabetics… View more
Author(s): Jason H Rogers , John R Laird Added: 3 years ago
Critical limb ischaemia (CLI) is defined as ischaemic rest pain requiring opiate analgesics, and ulceration or gangrene of the foot or toes attributable to arterial occlusive disease.1 In contrast to patients with claudication, those with CLI have resting arterial perfusion that is inadequate to sustain the metabolic demands of the distal bed. CLI has been formally graded within the current… View more
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Peripheral Artery Disease - General

Job title: Associate Professor of Vascular Surgery
Professor Varcoe is a vascular surgeon at Sydney’s Prince of Wales Hospitals where he is director of the operating theatres and of the Vascular Institute, one of Australia’s most prestigious clinical trials centres. His clinical practice specialises in the minimally invasive treatment of aortic conditions, carotid disease and the full gamut of occlusive arterial disease of the lower limb for… View more
Author(s): Marc Bosiers , Alessandra Puggioni , Koen Deloose , et al Added: 3 years ago
The treatment of critical limb ischaemia (CLI), a condition that may eventually lead to limb loss in a substantial number of patients, consumes a significant amount of healthcare resources. Distal bypass for limb salvage with autogenous conduit has been considered the procedure of choice for good-risk patients who also have suitable veins and distal target arteries for bypass. However, often one… View more
Author(s): Angelo Cioppa , Luigi Salemme , Vittorio Ambrosini , et al Added: 3 years ago
The incidence and prevalence of critical limb ischaemia (CLI) is progressively increasing, mainly because of the widespread incidence of diabetes mellitus and longer life expectancy in developed countries.1 Beyond lifestyle changes and medical therapy, arterial revascularisation is a mainstay in the management of patients with CLI due to below-the-knee (BTK) disease in order to improve functional… View more
Author(s): Yves S Alimi Added: 3 years ago
Peripheral arterial disease (PAD) increases in prevalence and incidence with advancing age, and the shifting demographics of an ageing general population is expected to increase the burden of PAD. Thus, there has been an increased focus on how best to manage this burden. If intervention is deemed necessary, surgery remains the gold standard for certain forms of lower-extremity occlusive disease… View more