Pacing, Defibrillators & Cardiac Resynchronisation Therapy

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A Quick Guide to Paravalvular Leak Closure

Sameer Gafoor, Jennifer Franke, Stefan Bertog, et al

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Permanent Pacemaker Implantation after TAVR

Marcel Weber, Jan-Malte Sinning, Christoph Hammerstingl, et al

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Unprotected Left Main Coronary Artery Disease

Samir R Kapadia, Stephen G Ellis, Nyal Borges,

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Real World Outcomes of Left Atrial Appendage Occlusion

Apostolos Tzikas, Darren Mylotte, Martin Bergmann,

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Optimising Stent Deployment in Contemporary Practice: The Role of…

Ashok Seth, Sajal Gupta, Vivudh Pratap Singh, et al

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Intraventricular Conduction Disturbances After TAVI

Shu-I Lin, Mizuki Miura, Ana Paula Tagliari, et al

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Advancing Syncope Diagnosis

Jayne Mudd, Jean-Claude Deharo, Rose Anne Kenny

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Webinar Trailer: AdaptivCRT™ algorithm for chamber and timing optimisation…

Carina Blomström-Lundqvist, Maurizio Lunati, Ulrike Neuhold

About

Cardiac pacing is a well-established therapeutic tool improving the survival and quality of life in patients. Indications for permanent cardiac pacing include sinus node dysfunction, intermittent and incomplete atrioventricular block, and bundle branch block.

Cardiac pacing, in conjunction with beta-blocker therapy, can potentially reduce the risk of bradycardia-dependent QT prolongation, decrease heart-rate irregularities and reduce repolarisation heterogeneity.

Cardiac resynchronisation therapy (CRT) with biventricular pacing is an effective therapy in patients with advanced heart failure (HF) – New York Heart Association (NYHA) Class III or IV, an ejection fraction (EF) 120 ms.

CRT has also been shown to be effective for the prevention of HF in relatively asymptomatic patients with wide QRS. However, CRT is underutilised among eligible patients. Approximately one-third of patients do not respond to CRT due to various factors, including anatomic difficulties and suboptimal lead placement. To increase the effectiveness of CRT, it has been hypothesised that pacing at multiple left ventricular (LV) sites may provide more effective resynchronisation.

In clinical studies, use of MultiPoint pacing in HF patients undergoing CRT has been associated with increased haemodynamic and clinical benefits compared with conventional pacing, particularly in patients with the least improvement from biventricular pacing.

Related Articles

Articles

Intraventricular Conduction Disturbances After TAVI

Shu-I Lin, Mizuki Miura, Ana Paula Tagliari,

Published:

Citation: Interventional Cardiology Review 2020;15:e11.

Unprotected Left Main Coronary Artery Disease

Samir R Kapadia, Stephen G Ellis, Nyal Borges,

Citation: Interventional Cardiology Review 2017;12(2):92–6.

Optimising Stent Deployment in Contemporary Practice: The Role of…

Ashok Seth, Sajal Gupta, Vivudh Pratap Singh,

Citation: Interventional Cardiology Review 2017;12(2):81–4.

A Quick Guide to Paravalvular Leak Closure

Sameer Gafoor, Jennifer Franke, Stefan Bertog,

Citation: Interventional Cardiology Review 2015;10(2):112–7