Coronary Physiology

About

Invasive coronary physiology is a key instrument in decision making for the interventional cardiologist.

Fractional flow reserve (FFR) has been well validated in chronic stable coronary artery disease. FFR is the ratio of the pressure distal to a lesion relative to the aorta pressure during maximal hyperaemia. Its practical applications are expanding into other clinical situations, including acute coronary syndrome, severe aortic stenosis and post percutaneous coronary intervention.

Instant wave-free ratio (iFR) is a resting index used to assess severity of an intracoronary stenosis. It measures the ratio of mean coronary pressure distal to a stenosis to the mean aortic pressure during an isolated period of diastole – the “wave-free period”.

It is an attractive alternative to FFR because it does not require hyperaemia, and therefore has a lower incidence of patient discomfort, side-effects, and shorter procedural time.

Related Articles

Articles

Coronary Physiology Derived from Invasive Angiography

Lavinia Gabara, Jonathan Hinton, Julian P Gunn,

Published:

Citation: Interventional Cardiology Review 2020;15:e06.

Contemporary Approach to Heavily Calcified Coronary Lesions

Carlotta Sorini Dini, Giulia Nardi, Francesca Ristalli,

Published:

Citation: Interventional Cardiology Review 2019;14(3):154–63.

Intracoronary Imaging and Physiological Assessment in Calcified Lesions

Yasushi Ueki, Tatsuhiko Otsuka, Kiyoshi Hibi,

Published:

Citation: Interventional Cardiology Review 2019;14(3):164–8.

Anomalous Coronary Arteries with a Malignant Course

Christoph Gräni, Philipp A Kaufmann, Stephan Windecker,

Published:

Citation: Interventional Cardiology Review 2019;14(2):83–8.